The letter is interspersed with poetry. De Missy writes that after reading Voltaire’s last letter four times, he had begun to reply only to realise that Voltaire had left Brussels for three months without telling him where he could write to him. He goes on to discuss devotion and religion, which he notes Voltaire calls less human than nature, arguing that nature is intended to make us know, love, and imitate the humanity of God. He writes that he thought it was superstition that Voltaire contested, and that he was doing what the devotees do by stripping religion of superstition. De Missy goes on to say that he will make a confession of faith that would not scandalise Voltaire, but that may annoy him, and that perhaps there is more sin in annoying one’s neighbour than in scandalising them. He then discusses the books Voltaire had asked him for, saying he had found German editions of the books of Wotton and Pancirolle but not English ones as Voltaire had requested. He then asks for details about Voltaire’s new tragey (likely Mahomet) which he has been told is very beautiful. He asks if the play has been printed and, if so, where it can be found. De Missy then turns to his own health and that of Voltaire, entreating him to work without tiring himself.