The MS is divided into the following sections:

• ‘Diatribe du Docteur Akakia, médecin du Pape: décret de l’Inquisition; et rapport des professeurs de Rome au sujet d’un prétendu Président. Rome 1753.’
  
• ‘Berlin du 16eme Decembre 1752’
• ‘Decret de l’Inquisition de Rome’
• ‘Augement des Professeurs du Collége de la Sapience’
• ‘Mémoire’, written in the hand of Collini with an autograph correction by Voltaire
• ‘Reponse de Mr de Voltaire à Mr de Maupertuis’
• ‘Avertisement qui a paru dans les gazettes litteraires et ordinaires de Leipzig’

The poem concerns the castration of young singers, and Pope Clement XIV’s attitudes towards this practice. The poem may have been written by Charles Bordes (1711-1781).

The text was printed in Le Second recueil de nouvelles pièces fugitives de M. de Voltaire (Geneva-Paris, 1762) p.cxxxii. The attribution to Voltaire is contested by Bengesco.

In the mémoire, Voltaire claims that his Histoire Universelle has been disfigured by Jean Néaulme in Berlin and Duchesne in Paris. He notes that it is not his fault if there have been unworthy popes, bad princes, and bad bishops, and neither is it his fault that people at court are ignorant. He asks the recipient to get rid of the existing copies of the work if possible, and asks to make public the purity of his conduct before the King, adding that he is threatened with an outburst from the Archibishop of Paris.